Elevated Prolactin Levels Observed Were Similar Between INVEGA HAFYERA™ and INVEGA TRINZA® (paliperidone palmitate)
Percentage of Patients With Increased Prolactin Levels Relative to Maintenance Baseline1
Like other drugs that antagonize dopamine D2 receptors, paliperidone elevates prolactin levels, and the elevation persists during chronic administration. Paliperidone has a prolactin-elevating effect similar to that seen with risperidone, a drug that is associated with higher levels of prolactin than other antipsychotic drugs.
Potentially Prolactin-related AEs Observed Were Generally Similar Between INVEGA HAFYERA™ and INVEGA TRINZA®
Percentage of Patients With Potentially Prolactin-related AEs2
REFERENCES: 1. INVEGA HAFYERA™ [Prescribing Information]. Titusville, NJ: Janssen Pharmaceuticals, Inc.; August 2021.